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Each sketch of HBO's seven-part comedy series, Life, Larry and the Pursuit of Unhappiness: An Almost History of America, starts with historical fact — then veers wildly, and enjoyably, off the rails.

Two major earthquakes in Venezuela have killed at least 164 people and left hundreds injured. And, President Trump canceled the signing of a massive bipartisan housing bill yesterday.

Louisiana has long struggled with maternal and infant mortality. In New Orleans, free home visits by nurses help spot medical problems early. It's a reproductive health policy with bipartisan support.

President Trump says he has signed two new orders targeting birthright citizenship. And, Iran is aiming to ban U.S. ships from the Strait of Hormuz.

Widespread protests in Iran earlier this year were met with a deadly crackdown by the regime. NPR has collected eyewitness accounts which paint an alarming picture of the extent of the killings.

A U.S. company in Rwanda has been providing medical supplies via drone. But even state-of-the-art technology can't overcome a weak health care infrastructure.

Listen to the best student podcasts about what "life, liberty and the pursuit of happiness" means for young people today.

If your doctor prescribes a GLP-1 medication for weight loss but your insurance won't cover it, you have options.

The left-handed MLB pitcher was 31 years old when he tore the ulnar collateral ligament in his pitching elbow in 1974, an injury that had been a death knell for pitchers' careers up to that point.

NPR's A Martinez speaks with Julian Shapiro-Barnum, the host of the popular series "Recess Therapy," about his new book, "How to Grow Up Without Becoming a Grown-Up."